| Term | Full Form | Definition | Meaning | Main Category | Subcategory | Country/ Region | Popularity |
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| SFS | Skyline Foundations & Structures | Business › Companies & Corporations |  |
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| SFS | Stepless Frequency Selection | Technology › Tech Terms |  |
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| SFS | Self-certifying File System | Computing › Data Storage | |
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| SFS | Sidwell Friends School | Academic & Science › Universities & Institutions |  |
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| SFS | Superior Feed System | Technology › Tech Terms | |
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| SFS | Subic Bay International Airport | Transport & Travel › Airport Codes |  |
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| SFS | Seoul Foreign School | Academic & Science › Universities & Institutions |  |
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| SFTP | Secure File Transfer Protocol | Computing › Protocols | |
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| SFTP | Screened Foiled Twisted Pair | Computing › Networking | |
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| SFX | Special Effects | Technology › Tech Terms | |
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| SFX | Sound Effects | Technology › Tech Terms | |
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| SFX | SelF-eXtracting | Computing › Compression & Encoding | |
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| SFX | Serial Femtosecond Crystallography | Technology › Tech Terms | |
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| SFX | Saint Francis Xavier | Society & Culture › Religion & Spirituality | |
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| SG | Singapore | Regional › Countries |  |
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| SG | Selena Gomez | Society & Culture › Celebrities & Famous | |
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| SG | Shooting Guard | Sports & Games › Basketball | |
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| Sg | Seaborgium | Academic & Science › Chemistry | |
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| SG | Spark Gap | Academic & Science › Electrical | |
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| SG | Sanspareils Greenlands | Business › Companies & Corporations | |
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| sg | Singapore (TLD) | Computing › Domain Names (TLD) | |
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| SG | Stevenage | Regional › Postal |  |
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| SG | Sensor Glucose | Medical › Healthcare | |
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| SG | Sega Genesis | Computing › Games & Entertainment | |
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| SG | Sonic Generations | Computing › Games & Entertainment | |
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