| Term | Full Form | Definition | Meaning | Main Category | Subcategory | Country/ Region | Popularity |
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| LS | Jet2 | Transport & Travel › Airline Codes |  |
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| LS | Lichen Sclerosus | Medical › Diseases & Conditions |  |
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| ls | Lesotho | Computing › Domain Names (TLD) |  |
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| LS | Lok Sabha | Governmental › Politics |  |
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| LS | Locus Sigilli | Governmental › Law & Legal | |
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| LS | Lung Surfactant | Medical › Biochemistry | |
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| LS | Leading Seaman | Governmental › Military | |
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| LS | Logistics Specialist | Governmental › Military |  |
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| LS | Long Snapper | Sports & Games › Football | |
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| LS | Limit Switch | Academic & Science › Electrical | |
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| LS | Lectori Salutem | Academic & Science › Language & Linguistics | |
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| LS | Liberalna Stranka | Governmental › Politics |  |
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| LS | light-second | Academic & Science › Units | |
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| LS | Lost Souls | Computing › Games & Entertainment | |
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| LS | Local Supercluster | Academic & Science › Astronomy & Space Science | |
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| LSAT | Law School Admission Test | Academic & Science › Exams & Tests | |
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| LSAT | Linux Security Auditing Tool | Computing › Security | |
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| LSB | Least Significant Bit | Computing › General Computing | |
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| LSB | Legacy Standard Bible | Society & Culture › Religion & Spirituality | |
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| LSB | Lower SideBand | Technology › Communication | |
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| LSB | Least Significant Byte | Computing › General Computing | |
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| LSB | Lithium-Sulfur Battery | Technology › Tech Terms | |
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| LSB | Liga Sudamericana de Básquetbol | Sports & Games › Basketball | |
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| LSB | Liga Superior de Baloncesto | Sports & Games › Basketball |  |
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| LSB | Legal Services Board | Governmental › Law & Legal | |
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